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Fluoxetine

Fluoxetine (also known by the tradenames Prozac, Sarafem)

(Trade Name:  Prozac)

Form: capsules or liquid.

Children: Not recommended for OCD - see below.
Adult dose: For obsessive-compulsive disorder: 20mg daily initially; if there is no improvement after several weeks, the dose may be increased but this may result in more side effects. Maximum dose 60mg daily.
Half-life: 1-3 days
Drug interactions: Monoamine oxidase inhibitors (MAOI) should not be given until at least five weeks after stopping Fluoxetine.

For use in children and young people: Fluoxetine should be only be used where there is significant comorbid depression, because of current regulatory requirements. For children and young people with OCD or BDD who also have significant depression, the NICE recommendations for the treatment of childhood depression should be followed and there should be specific monitoring for suicidal thoughts or behaviours.

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